Life Science & Health

Life science is a field of understanding the basic principles of sustaining life and seeks and provides application methods based on it. Life science is positioned not only as a basic field of study, but also as an important field that can overcome global issues. The search for sustainability in order to overcome hazards to mankind such as climate change, environmental pollution, and the human diseases, such as coronavirus pandemic is emerging as a major task in life science research. The Life science and Health division embraces six sessions that discuss topics in the area of emerging technologies in biomedical science, agriculture, cancer, environments Six sessions are organised at EKC 2022. 1. Sustainable Development in Biomedical Science and Technology 2. Emerging technologies to address agricultural issues with sustainability 3. Lifestyle Exposures and Cancer Prevention and Survival 4. Cutting edge techniques in molecular biology research 5. Our changing environment: Its molecular/cellular impact on biological systems and processes 6. Precision Medicine in Oncology: An Update

Programme Committee

DR. LYOO, Heyrhyoung (유혜령)
KU Leuven
heyrhyoung@gmail.com
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DR. RYU, Changseon (류창선)
KIST Europe Forschungsgesellschaft mbH
jacobryu@gmail.com
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Date / Time 2022-07-20 13:30   --   15:10
Room Joliette
Conveners / Chairs
DR. JEONG, Hyun-woo

Max Planck Institute for Molecular Biomedicine

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MR. YOON, Juyong

Korea Institute of Science and Technology Europe

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Synopsis
Artificial intelligence and machine learning are becoming dominant problem-solving techniques in many research areas. Also, next-generation sequencing as well as more developed single cell sequencing, and spatial sequencing techniques can offer deeper understanding of molecular mechanisms, phenotyping study, and solving complicated problems in life and health science. In this session, speakers will provide cutting edge techniques in the life sciences and its practical application.
Speakers
  • DR. YOON, Juyong (Korea Institute of Science and Technology Europe) [ 13:30 - 13:50 ]
    Title: AI-based computer vision for phenotypic screening
  • DR. JEONG, Hyun-woo (Max-planck Institute For Molecular Biomedicine, Germany) [ 13:50 - 14:10 ]
    Title: High-Throughput Single Cell RNA-Seq / Multi-Omics Analysis: Principles & Applications
  • MR. KIM, Yong Kuk (Eth Zurich) [ 14:10 - 14:30 ]
    Title: A deep-learning approach for automatically detecting gait events based on foot-marker kinematics in children with cerebral palsy -- what markers work best for what gait patterns?
  • MS. HUR, Sunyoung (Sorbonne Universite (paris) And Ntu (singapore)) [ 14:30 - 14:50 ]
    Title: Molecular Mechanism of Barnacle Adhesion : A structural Approach and Underlying Biochemistry
  • DR. LEE, Seung-hun (Seoul National University) [ 14:50 - 15:10 ]
    Title: How Many Times Should We Stir to Make a Cup of Dalgona Coffee? – Application of Statistical Analysis to Food Science
Date / Time 2022-07-20 15:20   --   18:40
Room Joliette
Conveners / Chairs
PROF. LIM, Hyun Soo

Sakaray University of Applied Science, Turkey, Professor

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Synopsis
High technoloy of medical device & drug is one of the most importance key technoloies of human life science and health in the 21st centry. It will increasingly play a decision role in international competition and enables sustainable growth in numerous braches of indusstry. We invite experts in this field to introduce cutting-edge medical devices capable of diagnosing and treating diseases and cutting-edge technologies in the field of drug development, and to introduce R&D trends internationally. In particular, we would like to introduce technology for early diagnosis of intractable cancer, and technology for effective diagnosis and treatment of metastatic cancer.
Speakers
  • PROF. MOK, K. Hun (Trinity College Dublin, The University Of Dublin, Ireland) [ 15:20 - 15:45 ]
    Title: A new biomolecular structure paradigm for anticancer therapeutics
  • MR. LEE, Jongmuk (Sol Inc.) [ 15:45 - 16:05 ]
    Title: A case of bio-application using a lens free image sensor
  • DR. AN, Jae-sung (Tu Delft, The Netherlands) [ 16:05 - 16:25 ]
    Title: Ultrasound Imaging System for the Bladder and Brain Monitoring
  • DR. KENAR LIM, Necla (Kocaeli University, Turkey) [ 16:25 - 16:45 ]
    Title: Development of Photodynamic Therapy Protocol for Oncology Patients
  • DR. SHIM, Jung-uk (University Of Leeds) [ 17:10 - 17:30 ]
    Title: KINETIC STUDY OF PROTEIN UNFOLDING USING MICRODROPLETS
  • DR. YOO, Sung Hyun (Iecb, Cbmn, Cnrs) [ 17:30 - 17:50 ]
    Title: Proteomimetic nanomaterials from self-assembly of unnatural folded oligomers
  • DR. HAN, Seungmin (Gurdon Institute, University Of Cambridge) [ 17:50 - 18:10 ]
    Title: A multi-disciplinary approach to understand mechanisms of stomach stem cell Heterogeneity
  • DR. CHOI, Ji-hyung (CEA Grenoble) [ 18:10 - 18:30 ]
    Title: Luminescent Lanthanide-based bioprobes for cellular imaging
Date / Time 2022-07-20 17:10   --   18:40
Room salle 36
Conveners / Chairs
DR. NAM, Kiwoong

INRAE, Chargé de Recherche

DR. CHO, Kwang-soo

WUR/RDA Liaison Office Representative

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Synopsis
Food security is threatened by changes in climate, the biological invasion of pest species, and the destruction of agricultural land. Traditionally, these problems have been tried to solve using chemical pesticides, monoculture, and genetic engineering in crops. The world is witnessing clear limitations on these methods, not only due to negative ecological impacts but also due to unsustainability. The world attempts to develop new sustainable and ecological methods against agricultural challenges through international collaborations and interdisciplinary approaches. Genomics, nanotechnology, artificial intelligence, and molecular biology are particularly useful for this purpose. Since an increasing proportion of agricultural issues causes global impact in ecology and economics, well-organized action-planes among international parties are often indispensable. However, many actions remain at regional or, at most, national levels. Communication among agricultural scientists working in different countries is one of the starting points to address main agricultural issues. This proposed section aims at finding common aspects in agricultural issues among agricultural scientists working in different countries, as well as identifying cross-disciplinary technologies that can be used as solutions.
Speakers
  • DR. CHO, Kwangsoo (Rural Development Adminstration, South Korea) [ 17:10 - 17:30 ]
    Title: Further development of Potato Late Blight Resistance Breeding technology and Phytophthora infestans monitoring in Korea
  • MS. JEONG, Sunyoung (Department Of Microbiology And Biotechnology, Max Rubner-institut, Federal Research Institute For Food And Nutrition, Kiel, Germany) [ 17:30 - 17:50 ]
    Title: Fresh produce as a potential vehicle for the spread of antibiotic resistant bacteria
  • MS. YANG, Suyeon (Laboratory Of Biophysics, Wageningen University And Research, Stippeneng 4, 6708 We Wageningen, The Netherlands) [ 17:50 - 18:05 ]
    Title: Multi-scale imaging of protein oxidation in food emulsions
  • DR. YANG, Jae-seong (Centre For Research In Agricultural Genomics (crag)) [ 18:05 - 18:25 ]
    Title: Beyond OMICs, quantitative understanding of gene expression
  • DR. NAM, Kiwoong (Inrae) [ 18:25 - 18:40 ]
    Title: The process of biological invasion in the fall armyworm
Date / Time 2022-07-21 11:00   --   12:30
Room Joliette
Conveners / Chairs
PROF. CHOI, Yoon-la

Department of Pathology & Translational Genomics, Samsung Medical Center; Sungkyunkwan University, School of Medicine, Seoul, So

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DR. NOH, Ka-won

Institute for Pathology, University Hospital Cologne; Position: Postdoctoral Researcher

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Synopsis
Background Healthcare is ever-changing and the usage of new technology is becoming more critical to generate relevant data and assist the adoption of precision medicine. Precision medicine is a type of medicine that prevents, diagnoses, or treats disease by using information about patient's genes or proteins. Precision medicine in cancer uses specific information about a person's tumor to help with diagnosis, treatment planning, determining how well treatment is working, and predicting prognosis. Purpose However, the use of "omics" technologies and large sample sizes has resulted in massive amounts of data sets, and their analysis has become a major bottleneck, necessitating sophisticated computational and statistical methods. The challenge now is to turn the multi-parametric taxonomic classification of a disease into better clinical decision-making by more precisely defining a disease, given the wealth of information for different diseases and its link to intrinsic biology. Through this session, we plan to shed light upon the new developments in the field of precision oncology. Significance We now know that biological properties vary greatly not only between cancers but also between patients. Given the large number of treatment options that exist in a particular cancer entity, modern oncology is currently facing multifactorial interpretations to develop the "best treatment" for individual patients. To confront this issue, various strategies are being developed, such as data integration between different diagnostic modalities or the use of artificial intelligence and machine learning to improve the traditional symptom-driven practice of medicine, allowing earlier interventions using advanced diagnostics and tailoring better and economically personalized treatments. Through this session, various aspects and challenges of the emerging methodologies will be discussed, thereupon paving a path towards precision medicine and better patient outcomes. Relevance to the theme of EKC2022 Precision medicine in oncology holds the promise of increased efficiency, improved care, and the elimination of ineffective treatments and costs. However, significant work remains to be done to prepare the oncological ecosystem to fully realize the potential of it. Through extensive exchanges of emerging technologies in devising individualized treatment plan for cancer patients, we hope to bridge the the valley of death across preclinical and clinical divide, leading to efficient and sustainable clinical responses in the field of translational oncology.
Speakers
  • PROF. BUETTNER, Reinhard (Institute Of Pathology And Center For Integrated Oncology, University Hospital Cologne, Germany) [ 11:00 - 11:30 ]
    Title: Molecular Diagnostics for Precision Medicine: The national Network Genomic Medicine (nNGM)
  • DR. PARK, Joohyun (Institute For Medical Genetics And Applied Genomics, University Of Tübingen , Tübingen, Germany) [ 11:30 - 11:50 ]
    Title: Genome sequencing in clinical setting: solving rare disorders and discovering new gene variants
  • DR. GUPTA, Varun (Lung Clinic Hemer) [ 11:50 - 12:10 ]
    Title: Role of neo-adjuvant Immunotherapy in resectable non-small cell lung cancer
  • MS. CHANG, Eun Sol (Saihst,sungkyunkwan University) [ 12:10 - 12:30 ]
    Title: Accumulation of mtDNA copy number is correlated with mtDNA variants and with poor prognosis in NSCLC
Date / Time 2022-07-21 13:30   --   15:00
Room Salle 50
Conveners / Chairs
PROF. LEE, Hyojung

Kyungpook National University

DR. CHOI, Sunhwa

National Institute for Mathemtical Sciences

Synopsis
There have emerged several coronaviruses, namely SARS-CoV, MERS-CoV, and SARS-CoV-2 within two decades. These coronaviruses as well as novel variant viruses are extremely dreadful and getting more serious as a global threthen. Moreover, the fast spread of misinformation about the outbreak causes worldwide panic. To prevent the spread of infectious disease, Republic of Korea has adopted a local quarantine strategy rather than a global lockdown to effectively prevent the spread of diseae while minimizing economic damage. In order to give a scientific information, Analysis of epidemiological data and mathematical modeling were used to predict the spread of COVID-19 and make policy decisions. In addition, mathematical modeling can be analyzed to evaluate the effectiveness of control interventions, including pharmaceiutical intervention such as vaccination and antiviral treatment and non-pharmaceiutical intervention such as social distancing, face mask use, contact tracing. In this session, we would like to introduce the situation of COVID-19 in Korea and the “K-quarantine” practiced at each period. Furthermore, we analyze the transmission dynamics along with control interventions of “K-quarantine” by usign mathematical modeling. Finally, we assesse the effect of th control strategies on the spread of infectious disease.
Speakers
  • DR. LEE, Jacob (Hallym University Kangnam Sacred Heart Hospital) [ 13:30 - 14:00 ]
    Title: Characteristics of COVID-19 variants and control policy of COVID-19 pandemic in Korea.
  • PROF. LEE, Hyojung (Kyungpook National University) [ 14:00 - 14:15 ]
    Title: Analysis of the impact of vaccination on the COVID-19 epidemic using mathematical and statistical modeling
  • PROF. LEE, Jeehyun (Yonsei University) [ 14:15 - 14:30 ]
    Title: Social mixing patterns and infectious disease modeling
  • PROF. KWON, Hee-dae (Inha University) [ 14:30 - 14:45 ]
    Title: Feedback control problem of an SIR model based on the Hamilton-Jacobi-Bellman equation
  • DR. CHOI, Yoon Hong (Uk Health Security Agency) [ 14:45 - 15:00 ]
    Title: Impact of COVID-19 social distancing measures on future incidence of invasive pneumococcal disease in England and Wales: a mathematical modelling study
Date / Time 2022-07-21 13:30   --   15:00
Room Joliette
Conveners / Chairs
PROF. KIM, Jeongseon

National Cancer Center, Korea

DR. NOH, Hwayoung

Leon Berard Cancer Center (CLB), Lyon, France

Synopsis
Cancer is a leading cause of death and a major issue of public health worldwide, indicating that it has risen to 19.3 million cases and 10 million cancer deaths in 2020 (Globocan). The International Agency for Research on Cancer (IARC-WHO) estimates that 1 in 5 people develop cancer during their lifetime, and 1 in 8 men and 1 in 11 women die from the disease, globally. However, about 40% of cancer cases and deaths are linked to modifiable lifestyle factors (e.g. smoking, alcohol, weight status, diet, physical activity, and exposures to environmental carcinogens), and thus would be preventable. The topic of the proposed session will be "Lifestyle Exposures and Cancer Prevention and Survival” to seek sustainable ways to prevent cancer and improve cancer survival. There will be discussions and presentations based on recent scientific evidence from outstanding scientists on this topic.
Speakers
  • DR. FREISLING, Heinz (International Agency For Research On Cancer (IARC/WHO)) [ 13:30 - 13:55 ]
    Title: Lifestyle exposures and cancer risk and survival: evidence from population-based cohort studies
  • PROF. KIM, Jeongseon (National Cancer Center) [ 13:55 - 14:20 ]
    Title: Association of the inflammatory balance of diet and lifestyle with colorectal cancer among Korean adults: a case–control study
  • MISS. SONG, Yura (Laboratory Of Stem Cells And Cancer, Université Libre De Bruxelles (ulb), Brussels, Belgium.) [ 14:20 - 14:40 ]
    Title: Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis.
  • DR. NOH, Hwayoung (Inserm U1296) [ 14:40 - 15:00 ]
    Title: The effect of diet-gut microbiota associations on human health: from metabolic health to cancer
Date / Time 2022-07-21 15:20   --   16:50
Room Joliette
Conveners / Chairs
DR. KWON, Jaedeok

University of Glasgow

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DR. KO, Hee Kyoung

Researcher, University of Reading, UK & Visiting Researcher, University of Oxford, UK

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Synopsis
In the sprit of this year’s EKC 2022 theme of “Pathways to Sustainability”, we examine – in molecular and cellular detail - how the processes, pathways and mechanisms in living systems are being impacted by exogenous inputs from the environment. The resulting outputs that are currently being observed appear to be far-and-wide, pervading all levels of life – from the population as a whole to the individual organsm, from the physiology of the organs to that of the tissues, from our cells to the molecular and structural details of our biomolecules. In the biomedical sciences, these profound changes may lead to changes in the immune system (as inflammation or auto-immunity), transcriptional activation, in ROS (reactive oxygen species) and cellular defense, cell proliferation (cancer), diabetes, or perhaps even in the area of mental health. What we learn in this session may provide us with clues from dealing with different types of toxic environmental pollutents to how these exogenous insults disrupt physiology and manytimes cause dieases. Our hope is that during this session, we will share constructive ideas and integrate knowledge from different fields, emerging with new ideas for new technologies.
Speakers
  • PROF. WOO, Euijeon (Kribb) [ 15:20 - 15:50 ]
    Title: Detection of hydrocarbon pollutant by the microbial enzyme DmpR and its structural activation mechanism
  • DR. JEONG, Jinyoung (Kribb) [ 15:50 - 16:10 ]
    Title: Recent studies on the biological effects of micro/nanoplastics in developing zebrafish
  • DR. YOO, Sungjae (Aix-marseille Université , Cnrs, Institut De Biologie Du Développement De Marseille, Umr 7288, Case 907, 13288 Marseille Cedex 09, France) [ 16:10 - 16:25 ]
    Title: The new players of gate control theory in chronic pain mechanism
  • DR. PARK, Dong Young (University Of Warwick) [ 16:25 - 16:40 ]
    Title: Environmental effect of air versus gas tamponade in the management of rhegmatogenous retinal detachment VR surgery
  • MISS. KIM, Ile (Max Rubner-institut) [ 16:40 - 16:50 ]
    Title: Distribution of antibiotic-resistant bacteria isolated from lettuce in South Korea